Cleanance
Cleanance Comedomed Anti-blemish concentrate
Fast-acting, durable efficacy***, high tolerance
Cleanance
Cleanance Comedomed Anti-blemish concentrate
Permanent
Tightens pores - Removes excess sebum - Reduces the appearance of imperfections
Cleanance Comedomed Concentrate, our best global solution for acne-prone skin that targets imperfections at the root, offering a durable effect with clinically proven results from seven days*. Highly tolerant for acne-prone skin. Safe for use by pregnant women.
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Effectiveness demonstrated within 7 days*.
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Fast-acting, durable efficacy***, high tolerance
Pregnant women - Young mothers - Teenagers - Adults
From 12 year(s)
Chest - face - back
Acne-prone skin
Anti-imperfections - Anti recurrence
Cleanance Comedomed Anti-blemish concentrate is our most advanced solution for acne-prone skin, whether it's sudden or even hormonal acne pimples, developed by Avène Dermatological Laboratories.
Powered by 25% of our patented active ingredient ComedoclastinTM**, extracted from Milk Thistle seeds, this solution targets imperfections at the root as they form and offer long-lasting results.
Clinically proven to reduce spots in seven days*, Cleanance Comedomed offers a durable action, with consistent use, up to one year***. Designed for oily skin, it is suitable for adults and teenagers from 12 years old. Its fluid, non-greasy texture ensures quick absorption, leaving the skin mattified.
Usable alone, in combination, or as a follow-up to acne medication, this non-comedogenic care guarantees high tolerance for sensitive skin. Safe for use by pregnant women.
Benefit
The revolutionary solution for acne-prone skin that reduces the appearance of spots within seven days* and provides a durable efficacy thanks to Comedoclastin™, a plant-based key ingredient extracted from Milk Thistle, with patented properties**.
Benefits
• EFFECTIVE: Effective on all types of imperfections of acne-prone skin (including inflammatory, blackheads, papules, pustules, etc.), thanks to its high concentration of 25% of our patented active ingredient: Comedoclastin™**, which acts at the root of imperfections to reduce and provide a long-lasting effect.
• FAST: Reduces the appearance of spots in as little as 7 days*. Offers a long-lasting efficacy***. For clearer skin and better comfort daily.
• HIGH TOLERANCE: Used alone or in combination with medical treatments, its tolerance by sensitive, acne-prone skin is clinically demonstrated*.
• SAFE: Safe for use by pregnant women.
*Used twice a day on the face, it offers a long-lasting effect on the appearance of blemishes. Efficacy demonstrated over 8 weeks, 37 subjects.
* Tolerance and efficacy study under dermatological control on 51 subjects, use of Cleanance Comedomed twice a day for 56 days.
** Patent registered.
*** Clinical study proving that the product povided a lasting efficacy for 85% of subjects from 1 year with 2 applications a day on the face, 54 subjects.
**IQVIA - Xponent PharmaOne - Acne market (83A1A) in pharmacies in France - Year 2021 - volume & value.
***Clinical scoring, twice a day on the face, 51 subjects.
*****International observational clinical study, 85% of patients without relapse at 1 year (according to the GEA >3 protocol definition of relapse requiring the introduction of a medicinal treatment – oral or local), 54 subjects, 2 applications per day of Cleanance Comedomed for 1 year.
**IQVIA - Xponent PharmaOne - Acne market (83A1A) in pharmacies in France - Year 2021 - volume & value.
***Clinical scoring, twice a day on the face, 51 subjects.
*****International observational clinical study, 85% of patients without relapse at 1 year (according to the definition of relapse in the GEA >3 protocol requiring the introduction of a medicinal treatment - oral or local), 54 subjects, 2 applications per day of Cleanance Comedomed for 1 year.
Environmental impact
Formula
Biodegradable formula*
Formulated to limit the impact on the aquatic environment***
*According to an OECD 301 test or a biodegradability index
*** According to an OECD 301 test and CLP classification of the formula
Packaging
Fully recyclable packaging
Manufacturing
Formulated with one or more raw materials from the circular economy
Manufactured and packaged in an environmentally certified facility****
Formula developed cold without any heating
****According to ISO 14001 and/or 50001
Transportation
Low CO2 impact of raw material transport (< 70 g CO2 eq. )
Societal impact
Product manufactured and packaged in a factory with high social compliance
Avène is a brand of the Pierre Fabre Group, certified at the highest Exemplary level of AFNOR Certification’s ‘Committed to CSR’ and ‘Responsibility Europe’ labels, thus consolidating a long-standing commitment to sustainable development.
Does not contain raw materials of animal origin
The Green Impact Index is a tool displaying the environmental and societal impact of cosmetics, dietary supplements and wellness and family health products, based on the methodology of the AFNOR Spec 2215. Developed thanks to the contribution of 22 companies, associations and federations, it assesses your products on more than 50 criteria for ever greater transparency!
Application
Frequency of use
2 times a day
Advice for use:
Spread 1 dose of Cleanance Comedomed on your fingertips, on a cleansed face.
• Start by dabbing it onto the T-zone and the cheeks.
• Use circular motions to boost penetration.
• Finish by smoothing on the cheeks and lower face.
Reapply morning and evening.
An expert tip:
Just one piece of advice: adopt a short but essential routine!
• 1 rigorous careful cleanse of the face or makeup removal: morning and evening!!!
• 1 anti-imperfection treatment: also morning and evening.
Skincare routine
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Ingredients
AVENE THERMAL SPRING WATER (AVENE AQUA). ISOPROPYL ALCOHOL. PEG-6. GLYCERIN. SILYBUM MARIANUM FRUIT EXTRACT. SILICA. POLYACRYLATE-13. POLYISOBUTENE. POLYSORBATE 20. SORBITAN ISOSTEARATE. WATER (AQUA)
The consumer is advised to systematically check the composition of the product before purchasing it.
Comedoclastin™
Avene thermal water
Results
• Long-lasting efficacy for 90%²
• Reduced the appearance of imperfections by -45% as of 2 months³, significant result versus control group
² International observational clinical study, 90% of patients without relapse at T6 months, (according to the definition of relapse in the protocol GEA≥3 requiring the introduction of an oral or local drug treatment), 48 subjects, 2 applications per day of Cleanance Comedomed alone for 6 months.
³ 36 subjects with slight to moderate imperfections. Comparative clinical study (group treated twice/day N=18), control group (N=18) for 56 days.
Which skin care routine should you adopt?
Identify what it really needs with the help of our experts and discover the most suitable skin care routine for you.